Organolithium-induced synthesis of acyclic unsaturated amino alcohols from epoxides of dihydropyrroles and tetrahydropyridines

The alkylative double ring-opening of Bus-protected 2,5-dihydropyrrole epoxides 13 and 29 with organolithiums to give 3-substituted 1-aminobut-3-en-2-ols 13-19 and 30-32 are described. Bus-protected tetrahydropyridine epoxide 38 reacts with organolithiums to give 4-substituted 1-aminobut-4-en-3-ols...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Hodgson, D, Miles, T, Witherington, J
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2003