Organolithium-induced synthesis of acyclic unsaturated amino alcohols from epoxides of dihydropyrroles and tetrahydropyridines

The alkylative double ring-opening of Bus-protected 2,5-dihydropyrrole epoxides 13 and 29 with organolithiums to give 3-substituted 1-aminobut-3-en-2-ols 13-19 and 30-32 are described. Bus-protected tetrahydropyridine epoxide 38 reacts with organolithiums to give 4-substituted 1-aminobut-4-en-3-ols...

وصف كامل

التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Hodgson, D, Miles, T, Witherington, J
التنسيق: Journal article
اللغة:English
منشور في: 2003
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author Hodgson, D
Miles, T
Witherington, J
author_facet Hodgson, D
Miles, T
Witherington, J
author_sort Hodgson, D
collection OXFORD
description The alkylative double ring-opening of Bus-protected 2,5-dihydropyrrole epoxides 13 and 29 with organolithiums to give 3-substituted 1-aminobut-3-en-2-ols 13-19 and 30-32 are described. Bus-protected tetrahydropyridine epoxide 38 reacts with organolithiums to give 4-substituted 1-aminobut-4-en-3-ols 39 and tetrahydropyridinol 40. © 2003 Elsevier Ltd. All rights reserved.
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spelling oxford-uuid:5a91d416-25d3-4350-b533-44a6177c12772022-03-26T17:16:29ZOrganolithium-induced synthesis of acyclic unsaturated amino alcohols from epoxides of dihydropyrroles and tetrahydropyridinesJournal articlehttp://purl.org/coar/resource_type/c_dcae04bcuuid:5a91d416-25d3-4350-b533-44a6177c1277EnglishSymplectic Elements at Oxford2003Hodgson, DMiles, TWitherington, JThe alkylative double ring-opening of Bus-protected 2,5-dihydropyrrole epoxides 13 and 29 with organolithiums to give 3-substituted 1-aminobut-3-en-2-ols 13-19 and 30-32 are described. Bus-protected tetrahydropyridine epoxide 38 reacts with organolithiums to give 4-substituted 1-aminobut-4-en-3-ols 39 and tetrahydropyridinol 40. © 2003 Elsevier Ltd. All rights reserved.
spellingShingle Hodgson, D
Miles, T
Witherington, J
Organolithium-induced synthesis of acyclic unsaturated amino alcohols from epoxides of dihydropyrroles and tetrahydropyridines
title Organolithium-induced synthesis of acyclic unsaturated amino alcohols from epoxides of dihydropyrroles and tetrahydropyridines
title_full Organolithium-induced synthesis of acyclic unsaturated amino alcohols from epoxides of dihydropyrroles and tetrahydropyridines
title_fullStr Organolithium-induced synthesis of acyclic unsaturated amino alcohols from epoxides of dihydropyrroles and tetrahydropyridines
title_full_unstemmed Organolithium-induced synthesis of acyclic unsaturated amino alcohols from epoxides of dihydropyrroles and tetrahydropyridines
title_short Organolithium-induced synthesis of acyclic unsaturated amino alcohols from epoxides of dihydropyrroles and tetrahydropyridines
title_sort organolithium induced synthesis of acyclic unsaturated amino alcohols from epoxides of dihydropyrroles and tetrahydropyridines
work_keys_str_mv AT hodgsond organolithiuminducedsynthesisofacyclicunsaturatedaminoalcoholsfromepoxidesofdihydropyrrolesandtetrahydropyridines
AT milest organolithiuminducedsynthesisofacyclicunsaturatedaminoalcoholsfromepoxidesofdihydropyrrolesandtetrahydropyridines
AT witheringtonj organolithiuminducedsynthesisofacyclicunsaturatedaminoalcoholsfromepoxidesofdihydropyrrolesandtetrahydropyridines