Cell-type-specific TEV protease cleavage reveals cohesin functions in Drosophila neurons
Cohesin is a highly conserved multisubunit complex that holds sister chromatids together in mitotic cells. At the metaphase to anaphase transition, proteolytic cleavage of the α kleisin subunit (Rad21) by separase causes cohesin's dissociation from chromosomes and triggers sister-chromatid disj...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2008
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