Within-host evolution of Burkholderia pseudomallei in four cases of acute melioidosis

Little is currently known about bacterial pathogen evolution and adaptation within the host during acute infection. Previous studies of Burkholderia pseudomallei, the etiologic agent of melioidosis, have shown that this opportunistic pathogen mutates rapidly both in vitro and in vivo at tandemly rep...

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Bibliographic Details
Main Authors: Price, E, Hornstra, H, Limmathurotsakul, D, Max, T, Sarovich, D, Vogler, A, Dale, J, Ginther, J, Leadem, B, Colman, R, Foster, J, Tuanyok, A, Wagner, D, Peacock, S, Pearson, T, Keim, P
Format: Journal article
Language:English
Published: Public Library of Science 2010