Elevated rates of protein secretion, evolution, and disease among tissue-specific genes.

Variation in gene expression has been held responsible for the functional and morphological specialization of tissues. The tissue specificity of genes is known to correlate positively with gene evolution rates. We show here, using large data sets, that when a gene is expressed highly in a small numb...

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Bibliographic Details
Main Authors: Winter, E, Goodstadt, L, Ponting, C
Format: Journal article
Language:English
Published: 2004