Dissection of the genetics of Parkinson's disease identifies an additional association 5' of SNCA and multiple associated haplotypes at 17q21.

We performed a genome-wide association study (GWAS) in 1705 Parkinson's disease (PD) UK patients and 5175 UK controls, the largest sample size so far for a PD GWAS. Replication was attempted in an additional cohort of 1039 French PD cases and 1984 controls for the 27 regions showing the stronge...

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Main Authors: Spencer, C, Plagnol, V, Strange, A, Gardner, M, Paisan-Ruiz, C, Band, G, Barker, R, Bellenguez, C, Bhatia, K, Blackburn, H, Blackwell, J, Bramon, E, Brown, M, Burn, D, Casas, J, Chinnery, P, Clarke, C, Corvin, A, Craddock, N, Deloukas, P, Edkins, S, Evans, J, Freeman, C, Gray, E, Hardy, J, Hudson, G, Hunt, S, Jankowski, J, Langford, C, Lees, A, Markus, H, Mathew, C, McCarthy, M, Morrison, K, Palmer, C, Pearson, J, Peltonen, L, Pirinen, M, Plomin, R, Potter, S, Rautanen, A, Sawcer, S, Su, Z, Trembath, R, Viswanathan, A, Williams, N, Morris, H, Donnelly, P, Wood, N
Format: Journal article
Language:English
Published: Oxford University Press 2011