Improving analysis of cognitive outcomes in cardiovascular trials using different statistical approaches

Background: The Mini-Mental State Examination (MMSE) and the Montreal Cognitive Assessment (MoCA) questionnaires are commonly used to measure global cognition in clinical trials. Because these scales are discrete and bounded with ceiling and floor effects and highly skewed, their analysis as continu...

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Bibliographic Details
Main Authors: Lee, SF, Whiteley, W, Bosch, J, Sherlock, L, Cukierman-Yaffe, T, O’Donnell, M, Eikelboom, JW, Gerstein, HC, Bangdiwala, SI, Muniz-Terrera, G
Format: Journal article
Language:English
Published: BioMed Central 2024