Studies on an N-terminal nucleophile hydrolase and enzymes of clavulanic acid biosynthesis
<p>(3R,5R)-Clavulanic acid is a clinically important inhibitor of Class A β-lactamases. Progress has been made in to establishing the steps of clavulanic acid biosynthesis leading to (3S,5S)-clavaminic acid. However, the mechanism by which (3S,5S)-clavaminic acid is converted to the penultimat...
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| Formato: | Thesis |
| Idioma: | English |
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2008
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