The tandem zinc-finger region of human ZHX adopts a novel C2H2 zinc finger structure with a C-terminal extension.

Binding of the nuclear factor-Y complex (NF-Y) to the inverted CCAAT-box interferes with transcription activation through nucleosome reorganization. The three homologous proteins forming the zinc-fingers and homeoboxes (ZHX) family interact with the activation domain of NF-Ya to repress transcriptio...

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Bibliographic Details
Main Authors: Wienk, H, Lammers, I, Hotze, A, Wu, J, Wechselberger, R, Owens, R, Stammers, D, Stuart, D, Kaptein, R, Folkers, G
Format: Journal article
Language:English
Published: 2009