Human deficiencies of fucosylation and sialylation affecting selectin ligands.
Selectins are carbohydrate-binding adhesion molecules that are required for leukocyte trafficking to secondary lymphoid organs and to sites of infection. They interact with fucosylated and sialylated ligands bearing sialyl-Lewis X as a minimal carbohydrate structure. With this in mind, it should be...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2012
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