Cell specific expression of human Bruton's agammaglobulinemia tyrosine kinase gene (Btk) is regulated by Sp1- and Spi-1/PU.1-family members.

Bruton's agammaglobulinemia tyrosine kinase (Btk) is a cytoplasmic tyrosine kinase involved in the human disease X-linked agammaglobulinemia (XLA). The gene is expressed in all hematopoietic cells with the exception of T-cells and plasma cells. For this expression pattern the first 280 bp upstr...

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Detalhes bibliográficos
Principais autores: Müller, S, Sideras, P, Smith, C, Xanthopoulos, K
Formato: Journal article
Idioma:English
Publicado em: 1996