Demonstration of immunologic memory using serogroup C meningococcal glycoconjugate vaccine.

BACKGROUND: Studies of glycoconjugate vaccines have traditionally used an immune challenge with a plain polysaccharide vaccine to demonstrate immunologic memory. Plain polysaccharide vaccines are poorly immunogenic in children and can induce subsequent immunologic hyporesponsiveness. We therefore as...

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Bibliographic Details
Main Authors: Snape, MD, Maclennan, J, Lockhart, S, English, M, Yu, L, Moxon, R, Pollard, A
Format: Journal article
Language:English
Published: 2009