Genetic modifiers of CHEK2*1100delC-associated breast cancer risk.

Genetic modifiers of CHEK2*1100delC-associated breast cancer risk.

<h4>Purpose</h4> <p>CHEK2*1100delC is a founder variant in European populations that confers a two- to threefold increased risk of breast cancer (BC). Epidemiologic and family studies have suggested that the risk associated with CHEK2*1100delC is modified by other genetic factors...

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Main Authors: Muranen, T, Greco, D, Blomqvist, C, Aittomäki, K, Khan, S, Hogervorst, F, Verhoef, S, Pharoah, P, Dunning, A, Shah, M, Luben, R, Bojesen, S, Nordestgaard, B, Schoemaker, M, Swerdlow, A, García-Closas, M, Figueroa, J, Dörk, T, Bogdanova, N, Hall, P, Li, J, Khusnutdinova, E, Bermisheva, M, Kristensen, V, Borresen-Dale, A, NBCS Investigators, Peto, J, Dos Santos Silva, I, Couch, F, Olson, J, Hillemans, P, Park-Simon, T, Brauch, H, Hamann, U, Burwinkel, B, Marme, F, Meindl, A, Schmutzler, R, Cox, A, Cross, S, Sawyer, E, Tomlinson, I, Lambrechts, D, Moisse, M, Lindblom, A, Margolin, S, Hollestelle, A, Martens, J, Fasching, P, Beckmann, M, Andrulis, I, Knight, J, kConFab/AOCS Investigators, Anton-Culver, H, Ziogas, A, Giles, G, Milne, R, Brenner, H, Arndt, V, Mannermaa, A, Kosma, V, Chang-Claude, J, Rudolph, A, Devilee, P, Seynaeve, C, Hopper, J, Southey, M, John, E, Whittemore, A, Bolla, M, Wang, Q, Michailidou, K, Dennis, J, Easton, D, Schmidt, M, Nevanlinna, H
Format: Journal article
Sprog:English
Udgivet: Nature Publishing Group 2016

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