Temperature-dependent folding allows stable dimerization of secretory and virus-associated E proteins of Dengue and Zika viruses in mammalian cells

Dengue and Zika are two of the most important human viral pathogens worldwide. In both cases, the envelope glycoprotein E is the main target of the antibody response. Recently, new complex quaternary epitopes were identified which are the consequence of the arrangement of the antiparallel E dimers o...

Full description

Bibliographic Details
Main Authors: Slon Campos, J, Marchese, S, Rana, J, Mossenta, M, Poggianella, M, Bestagno, M, Burrone, O
Format: Journal article
Language:English
Published: Nature Publishing Group 2017