Mathematical modelling of the use of macrophages as vehicles for drug delivery to hypoxic tumour sites.
Poor drug delivery and low rates of cell proliferation are two factors associated with hypoxia that diminish the efficacy of many chemotherapeutic drugs. Since macrophages are known to migrate specifically towards, and localize within, hypoxic tumour regions, a promising resolution to these problems...
| Main Authors: | , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2004
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