Neuropathologic toxicity of artemisinin derivatives in a mouse model.

Intramuscular administration of high doses of artemether and arteether to experimental mammals produces selective damage to brain stem centers involved predominantly in auditory processing and vestibular reflexes. The relationship between clinical signs of neurotoxicity and neuropathologic toxicity...

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Bibliographic Details
Main Authors: Nontprasert, A, Pukrittayakamee, S, Dondorp, A, Clemens, R, Looareesuwan, S, White, N
Format: Journal article
Language:English
Published: 2002