Comparison of methods for transcriptome imputation through application to two common complex diseases

Transcriptome imputation has become a popular method for integrating genotype data with publicly available expression data to investigate the potentially causal role of genes in complex traits. Here, we compare three approaches (PrediXcan, MetaXcan and FUSION) via application to genome-wide associat...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Fryett, J, Inshaw, J, Morris, A, Cordell, H
Format: Journal article
Język:English
Wydane: Nature Publishing Group 2018