Comparison of methods for transcriptome imputation through application to two common complex diseases

Transcriptome imputation has become a popular method for integrating genotype data with publicly available expression data to investigate the potentially causal role of genes in complex traits. Here, we compare three approaches (PrediXcan, MetaXcan and FUSION) via application to genome-wide associat...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Fryett, J, Inshaw, J, Morris, A, Cordell, H
Μορφή: Journal article
Γλώσσα:English
Έκδοση: Nature Publishing Group 2018