Kinetochore-microtubule error correction is driven by differentially regulated interaction modes

For proper chromosome segregation, sister kinetochores must interact with microtubules from opposite spindle poles (bi-orientation). To establish bi-orientation, aberrant kinetochore-microtubule attachments are disrupted (error correction) by aurora B kinase (Ipl1 in budding yeast). Paradoxically, d...

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Manylion Llyfryddiaeth
Prif Awduron: Kalantzaki, M, Kitamura, E, Zhang, T, Mino, A, Novák, B, Tanaka, T
Fformat: Journal article
Iaith:English
Cyhoeddwyd: Nature Publishing Group 2015