Kinetochore-microtubule error correction is driven by differentially regulated interaction modes
For proper chromosome segregation, sister kinetochores must interact with microtubules from opposite spindle poles (bi-orientation). To establish bi-orientation, aberrant kinetochore-microtubule attachments are disrupted (error correction) by aurora B kinase (Ipl1 in budding yeast). Paradoxically, d...
Prif Awduron: | , , , , , |
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Fformat: | Journal article |
Iaith: | English |
Cyhoeddwyd: |
Nature Publishing Group
2015
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