Ultra-sensitive class I tetramer analysis reveals previously undetectable populations of antiviral CD8+ T cells.

A major breakthrough in cellular immunology has been the development of HLA class I tetramers to analyze CD8(+) T cell responses. However, in many situations, including persistent virus infection, specific T cell responses are rarely detected using this technology. This raises the question of whethe...

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Bibliographic Details
Main Authors: Barnes, E, Ward, S, Kasprowicz, V, Dusheiko, G, Klenerman, P, Lucas, M
Format: Journal article
Language:English
Published: 2004