Effects of endothelin-1 in the isolated heart in ischemia/reperfusion and hypoxia/reoxygenation injury.

The effects of the vasoconstrictor peptide endothelin-1 were examined in the isolated heart during hypoxia, reoxygenation and reperfusion. Isovolumic rat hearts were perfused with Krebs-Henseleit buffer at constant pressure. Cumulative dose-response curves were obtained for endothelin-1 boluses of 0...

Full description

Bibliographic Details
Main Authors: Neubauer, S, Zimmermann, S, Hirsch, A, Pulzer, F, Tian, R, Bauer, W, Bauer, B, Ertl, G
Format: Journal article
Language:English
Published: 1991