Effects of endothelin-1 in the isolated heart in ischemia/reperfusion and hypoxia/reoxygenation injury.
The effects of the vasoconstrictor peptide endothelin-1 were examined in the isolated heart during hypoxia, reoxygenation and reperfusion. Isovolumic rat hearts were perfused with Krebs-Henseleit buffer at constant pressure. Cumulative dose-response curves were obtained for endothelin-1 boluses of 0...
Main Authors: | Neubauer, S, Zimmermann, S, Hirsch, A, Pulzer, F, Tian, R, Bauer, W, Bauer, B, Ertl, G |
---|---|
Format: | Journal article |
Language: | English |
Published: |
1991
|
Similar Items
-
Effects of endothelin-1 in the isolated heart under ischemic and cardioplegic conditions.
by: Neubauer, S, et al.
Published: (1990) -
Endothelin-1 contributes to ischemia/reperfusion injury in isolated rat heart-attenuation of ischemic injury by the endothelin-1 antagonists BQ123 and BQ610.
by: Han, H, et al.
Published: (1995) -
Effects of endothelin-1 in isolated perfused rat heart.
by: Neubauer, S, et al.
Published: (1990) -
Endothelin-1 increases susceptibility of isolated rat hearts to ischemia/reperfusion injury by reducing coronary flow.
by: Groot, d, et al.
Published: (1998) -
Protective effect of the specific endothelin-1 antagonist BQ610 on mechanical function and energy metabolism during ischemia/reperfusion injury in isolated perfused rat hearts.
by: Illing, B, et al.
Published: (1996)