Mixed adjuvant formulations reveal a new combination that elicit antibody response comparable to Freund's adjuvants

Adjuvant formulations capable of inducing high titer and high affinity antibody responses would provide a major advance in the development of vaccines to viral infections such as HIV-1. Although oil-in-water emulsions, such as Freund's adjuvant (FCA/FIA), are known to be potent, their toxicity...

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Hlavní autoři: Lai, R, Seaman, MS, Tonks, P, Wegmann, F, Seilly, D, Frost, S, Labranche, C, Montefiori, D, Dey, A, Srivastava, I, Sattentau, Q, Barnett, S, Heeney, J
Médium: Journal article
Jazyk:English
Vydáno: Public Library of Science 2012