Nuclei sorting-based genome-wide CRISPR screens to identify novel regulators of hepatic insulin signalling

<p>Insulin is the central anabolic hormone in the human body. By modulating rates of hepatic glucose output and glucose uptake into skeletal muscle and adipose tissue, it is at the core of blood glucose homeostasis, ensuring normoglycaemia during fasting and feeding. The liver is one of the th...

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Bibliographic Details
Main Author: Martin Perez, E
Other Authors: Klemm, R
Format: Thesis
Language:English
Published: 2024
Subjects: