The influence of serum cytokines and growth factors on osteoclast formation in Paget's disease.

BACKGROUND: Osteoclasts are multinucleated cells (MNCs) that form from circulating mononuclear precursors in the presence of the receptor activator of nuclear factor kappa B-ligand (RANKL) and macrophage-colony stimulating factor (M-CSF). AIM: To determine whether cytokines and growth factors influe...

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Bibliographic Details
Main Authors: Neale, S, Schulze, E, Smith, R, Athanasou, N
Format: Journal article
Language:English
Published: 2002