Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1H.

Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1H.

A genetically reshaped human IgG1 monoclonal antibody (CAMPATH-1H) was used to treat two patients with non-Hodgkin lymphoma. Doses of 1-20 mg daily were given intravenously for up to 43 days. In both patients lymphoma cells were cleared from the blood and bone marrow and splenomegaly resolved. One p...

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Dades bibliogràfiques
Autors principals:	Hale, G, Dyer, M, Clark, MR, Phillips, J, Marcus, R, Riechmann, L, Winter, G, Waldmann, H
Format:	Journal article
Idioma:	English
Publicat:	1988

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