Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1H.

Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1H.

A genetically reshaped human IgG1 monoclonal antibody (CAMPATH-1H) was used to treat two patients with non-Hodgkin lymphoma. Doses of 1-20 mg daily were given intravenously for up to 43 days. In both patients lymphoma cells were cleared from the blood and bone marrow and splenomegaly resolved. One p...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς:	Hale, G, Dyer, M, Clark, MR, Phillips, J, Marcus, R, Riechmann, L, Winter, G, Waldmann, H
Μορφή:	Journal article
Γλώσσα:	English
Έκδοση:	1988

Παρόμοια τεκμήρια

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Reshaping human antibodies for therapy.
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Prevention of immune-mediated corneal graft destruction with the anti-lymphocyte monoclonal antibody, CAMPATH-1H.
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Reactivity of rat monoclonal antibody CAMPATH-1 with human leukaemia cells and its possible application for autologous bone marrow transplantation.
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CAMPATH-1H in inflammatory arthritis.
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T cell depletion with CAMPATH-1 in allogeneic bone marrow transplantation.
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Recent results using CAMPATH-1 antibodies to control GVHD and graft rejection.
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ALLOGENEIC BONE-MARROW TRANSPLANTATION FOR LEUKEMIA USING CAMPATH-1 MONOCLONAL-ANTIBODIES AND POSTTRANSPLANT ALLOIMMUNIZATION WITH DONOR LYMPHOCYTES
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CAMPATH-IH in multiple sclerosis.
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Campath-1 Abs 'in the bag' for hematological malignancies: the Cape Town experience.
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Alemtuzumab (Campath-1H) for treatment of lymphoid malignancies in the age of nonmyeloablative conditioning?
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