Remission induction in non-Hodgkin lymphoma with reshaped human monoclonal antibody CAMPATH-1H.
A genetically reshaped human IgG1 monoclonal antibody (CAMPATH-1H) was used to treat two patients with non-Hodgkin lymphoma. Doses of 1-20 mg daily were given intravenously for up to 43 days. In both patients lymphoma cells were cleared from the blood and bone marrow and splenomegaly resolved. One p...
Main Authors: | , , , , , , , |
---|---|
格式: | Journal article |
语言: | English |
出版: |
1988
|