POLCAM: instant molecular orientation microscopy for the life sciences

Current methods for single-molecule orientation localization microscopy (SMOLM) require optical setups and algorithms that can be prohibitively slow and complex, limiting widespread adoption for biological applications. We present POLCAM, a simplified SMOLM method based on polarized detection using...

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Main Authors: Bruggeman, E, Zhang, O, Needham, L, Körbel, M, Daly, S, Cheetham, M, Peters, R, Wu, T, Klymchenko, AS, Davis, SJ, Paluch, EK, Klenerman, D, Lew, MD, O’Holleran, K, Lee, SF
格式: Journal article
语言:English
出版: Nature Research 2024