Schwann cell nodal membrane disruption triggers bystander axonal degeneration in a Guillain-Barré syndrome mouse model
In Guillain-Barré syndrome (GBS), both axonal and demyelinating variants can be mediated by complement-fixing anti–GM1 ganglioside autoantibodies that target peripheral nerve axonal and Schwann cell (SC) membranes, respectively. Critically, the extent of axonal degeneration in both variants dictates...
Main Authors: | McGonigal, R, Campbell, CI, Barrie, JA, Yao, D, Cunningham, ME, Crawford, CL, Rinaldi, S, Rowan, EG, Willison, HJ |
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格式: | Journal article |
語言: | English |
出版: |
American Society for Clinical Investigation
2022
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