Iron-deficiency anemia results in transcriptional and metabolic remodeling in the heart toward a glycolytic phenotype

Iron deficiency is the most prevalent micronutrient disorder globally. When severe, iron deficiency leads to anemia, which can be deleterious to cardiac function. Given the central role of iron and oxygen in cardiac biology, multiple pathways are expected to be altered in iron-deficiency anemia, and...

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Bibliographic Details
Main Authors: Chung, YJ, Swietach, P, Curtis, MK, Ball, V, Robbins, PA, Lakhal-Littleton, S
Format: Journal article
Language:English
Published: Frontiers Media 2021