Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis.

Selective expression of connective tissue growth factor in fibroblasts in vivo promotes systemic tissue fibrosis.

OBJECTIVE: Connective tissue growth factor (CTGF) is a cysteine-rich secreted matricellular protein involved in wound healing and tissue repair. Enhanced and prolonged expression of CTGF has been associated with tissue fibrosis in humans. However, questions remain as to whether CTGF expression alon...

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Detalhes bibliográficos
Principais autores:	Sonnylal, S, Shi-Wen, X, Leoni, P, Naff, K, Van Pelt, C, Nakamura, H, Leask, A, Abraham, D, Bou-Gharios, G, de Crombrugghe, B
Formato:	Journal article
Idioma:	English
Publicado em:	2010

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