Inference of multisite phosphorylation rate constants and their modulation by pathogenic mutations

Multisite protein phosphorylation plays a critical role in cell regulation [1-3]. It is widely appreciated that the functional capabilities of multisite phosphorylation depend on the order and kinetics of phosphorylation steps, but kinetic aspects of multisite phosphorylation remain poorly understoo...

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Bibliographic Details
Main Authors: Yeung, E, McFann, S, Marsh, L, Dufresne, E, Filippi, S, Harrington, HA, Shvartsman, SY, Wühr, M
Format: Journal article
Language:English
Published: Elsevier 2020