Feedback control of regulatory T cell homeostasis by dendritic cells in vivo.

CD4(+)CD25(+)Foxp3(+) natural regulatory T cells (T reg cells) maintain self-tolerance and suppress autoimmune diseases such as type 1 diabetes and inflammatory bowel disease (IBD). In addition to their effects on T cells, T reg cells are essential for maintaining normal numbers of dendritic cells (...

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Bibliographic Details
Main Authors: Darrasse-Jèze, G, Deroubaix, S, Mouquet, H, Victora, G, Eisenreich, T, Yao, K, Masilamani, R, Dustin, M, Rudensky, A, Liu, K, Nussenzweig, M
Format: Journal article
Language:English
Published: 2009