Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented by HLA-B27.

Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented by HLA-B27.

OBJECTIVE: HLA-B27 and endoplasmic reticulum aminopeptidase 1 (ERAP1) are the two strongest genetic factors predisposing to ankylosing spondylitis (AS). A key aminopeptidase in class I major histocompatibility complex presentation, ERAP1 potentially contributes to the pathogenesis of AS by altering...

Полное описание

Библиографические подробности
Главные авторы:	Chen, L, Fischer, R, Peng, Y, Reeves, E, McHugh, K, Ternette, N, Hanke, T, Dong, T, Elliott, T, Shastri, N, Kollnberger, S, James, E, Kessler, B, Bowness, P
Формат:	Journal article
Язык:	English
Опубликовано:	2014

Схожие документы

Endoplasmic reticulum aminopeptidase 1 (ERAP1) plays a critical role in determining the length and sequence of peptides bound and presented by HLA-B27
по: Chen, L, и др.
Опубликовано: (2013)

INVESTIGATING THE ROLE OF ENDOPLASMIC RETICULUM AMINOPEPTIDASE-1 IN ANKYLOSING SPONDYLITIS
по: Chen, L, и др.
Опубликовано: (2012)

ENDOPLASMIC RETICULUM AMINOPEPTIDASE-1 (ERAP1) PLAYS A CRITICAL ROLE IN PEPTIDE BINDING AND ANTIGEN PRESENTATION BY HLA-B27
по: Chen, L, и др.
Опубликовано: (2012)

INVESTIGATING THE ROLE OF ENDOPLASMIC RETICULUM AMINOPEPTIDASE-1 (ERAP1) IN ANKYLOSING SPONDYLITIS
по: Chen, L, и др.
Опубликовано: (2010)

INVESTIGATING THE ROLE OF ENDOPLASMIC RETICULUM AMINOPEPTIDASE-1 (ERAP1) IN ANKYLOSING SPONDYLITIS
по: Chen, L, и др.
Опубликовано: (2010)

Identification of an unconventional sub-peptidome bound to the Behçet's disease - associated HLA-B*51:01 that is regulated by endoplasmic reticulum aminopeptidase 1 (ERAP1)
по: Chen, L, и др.
Опубликовано: (2020)

To Be or Not to Be: The Case of Endoplasmic Reticulum Aminopeptidase 2
по: Piotr Kuśnierczyk
Опубликовано: (2022-06-01)

Direct visualisation of HLA-B27 forms in cell lines and Spondyloarthropathy tissues
по: Rysnik, O, и др.
Опубликовано: (2013)

EXPRESSION OF HLA-B27 HEAVY CHAIN FORMS IN ANKYLOSING SPONDYLITIS AND HLA-B27 POSITIVE CELL LINES
по: Rysnik, O, и др.
Опубликовано: (2012)

HLA-B-27 heavy chain homodimer formation and natural killer cell family interaction - comparison of two HLA-B-27 subtypes in vitro
по: Giles, J, и др.
Опубликовано: (2008)

The pathogenesis of spondyloarthritides - HLA-B-27 homodimer expression on human monocyte/macrophage cell lines
по: McHugh, K, и др.
Опубликовано: (2008)

Silencing or inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) suppresses free heavy chain expression and Th17 responses in ankylosing spondylitis.
по: Chen, L, и др.
Опубликовано: (2015)

Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming.
по: Kochan, G, и др.
Опубликовано: (2011)

Impact of ACE and Endoplasmic Reticulum Aminopeptidases Polymorphisms on COVID-19 Outcome
по: Amany A. Ghazy, и др.
Опубликовано: (2023-01-01)

HLA-B27 HEAVY CHAIN DIMER EXPRESSION IN SPONDYLOARTHRITIS
по: Rysnik, O, и др.
Опубликовано: (2012)

HLA-B27 homodimers differ in their interactions with LILRB1, LILRB2, KIR3DL1 and KIR3DL2 compared to HLA-B27 heterotrimers
по: Giles, J, и др.
Опубликовано: (2010)

Human leukocyte antigen B polymorphism and association between HLA‐B27 and endoplasmic reticulum aminopeptidase 1 rs30187 SNP in patients with ankylosing spondylitis in Bangladesh
по: Md Kamrul H. Sajib, и др.
Опубликовано: (2022-03-01)

Endoplasmic reticulum aminopeptidase-1 polymorphism increases the risk of rheumatoid arthritis
по: Akbulut Ekrem, и др.
Опубликовано: (2022-03-01)

Molecular Characterisation Of The Killer Cell Immunoglobulin-Like Receptor 3DL2 Binding To Aberrant HLA-B27 Heavy Chains In Spondyloarthritis
по: Hatano, H, и др.
Опубликовано: (2013)

The KIRs of HLA-B27: the role of HLA-B27 KIR interactions in infection and spondyloarthritis
по: Wong-Baeza, I, и др.
Опубликовано: (2011)

THE ARTHRITIS-ASSOCIATED HLA-B(star)27:05 FORMS MORE CELL SURFACE B27 DIMER AND FREE HEAVY CHAIN LIGANDS FOR KIR3DL2 AND LILRB2 IMMUNORECEPTORS THAN HLA(star)B27:09
по: Shaw, J, и др.
Опубликовано: (2013)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
по: Bowness, P, и др.
Опубликовано: (2010)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
по: Bowness, P, и др.
Опубликовано: (2010)

THE ROLE OF HLA-B27 KIR3DL2 INTERACTIONS IN THE PATHOGENESIS OF SPONDYLOARTHRITIS
по: Kollnberger, S, и др.
Опубликовано: (2012)

Factors determining the cell surface expression of a novel HLA-B27 epitope
по: McHugh, K, и др.
Опубликовано: (2010)

The link between HLA-B27 and SpA--new ideas on an old problem.
по: McHugh, K, и др.
Опубликовано: (2012)

Identification and characterisation of cell surface HLA-B27 homodimers
по: Bird, L, и др.
Опубликовано: (2002)

HLA-B27 FORMS HEAVY CHAIN HOMODIMERS IN VITRO AND IN VIVO THAT BIND TO CELLULAR RECEPTORS INCLUDING LILR AND KIR FAMILY MEMBERS
по: McHugh, K, и др.
Опубликовано: (2010)

Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply.
по: McHugh, K, и др.
Опубликовано: (2014)

DIRECT VISUALIZATION OF HLA-B27 FORMS IN CELL LINES AND SPONDYLOARTHROPATHY TISSUES
по: Rysnik, O, и др.
Опубликовано: (2013)

Interaction of HLA-B27 homodimers with KIR3DL1 and KIR3DL2, unlike HLA-B27 heterotrimers, is independent of the sequence of bound peptide.
по: Kollnberger, S, и др.
Опубликовано: (2007)

Endoplasmic reticulum aminopeptidase 2 regulates CD4+ T cells pyroptosis in rheumatoid arthritis
по: Jianhua Zhang, и др.
Опубликовано: (2024-01-01)

Association study of polymorphisms of endoplasmic reticulum aminopeptidase 1 gene with preeclampsia in Chinese populations
по: Cui Ma, и др.
Опубликовано: (2021-08-01)

Endoplasmic reticulum aminopeptidase-1 functions regulate key aspects of the innate immune response.
по: Yasser A Aldhamen, и др.
Опубликовано: (2013-01-01)

Residue Cys-67 of HLA-B27 contributes to antigen presentation and T cell recognition of HLA-B27 restricted T cell epitopes.
по: Appel, H, и др.
Опубликовано: (2004)

Functional characterisation of HLA-B27 in autoimmunity
по: Kollnberger, S, и др.
Опубликовано: (2001)

HLA-B27 transgenic rodents express cell surface HLA-B27 heavy chain homodimers and multimers.
по: Bowness, P, и др.
Опубликовано: (2003)

Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling.
по: Bird, L, и др.
Опубликовано: (2003)

EnRAPtured: Is Endoplasmic Reticulum Aminopeptidase a New Clue to the Pathogenesis and ThERAPy of Uveitis?
по: James T. Rosenbaum, MD, и др.
Опубликовано: (2021-09-01)

Association between Endoplasmic Reticulum Aminopeptidase-1 (ERAP-1) and Susceptibility to Ankylosing Spondylitis in Iran
по: Mahdi Mahmoudi, и др.
Опубликовано: (2012-12-01)