Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented by HLA-B27.

Critical role of endoplasmic reticulum aminopeptidase 1 in determining the length and sequence of peptides bound and presented by HLA-B27.

OBJECTIVE: HLA-B27 and endoplasmic reticulum aminopeptidase 1 (ERAP1) are the two strongest genetic factors predisposing to ankylosing spondylitis (AS). A key aminopeptidase in class I major histocompatibility complex presentation, ERAP1 potentially contributes to the pathogenesis of AS by altering...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Chen, L, Fischer, R, Peng, Y, Reeves, E, McHugh, K, Ternette, N, Hanke, T, Dong, T, Elliott, T, Shastri, N, Kollnberger, S, James, E, Kessler, B, Bowness, P
स्वरूप:	Journal article
भाषा:	English
प्रकाशित:	2014

समान संसाधन

Endoplasmic reticulum aminopeptidase 1 (ERAP1) plays a critical role in determining the length and sequence of peptides bound and presented by HLA-B27
द्वारा: Chen, L, और अन्य
प्रकाशित: (2013)

INVESTIGATING THE ROLE OF ENDOPLASMIC RETICULUM AMINOPEPTIDASE-1 IN ANKYLOSING SPONDYLITIS
द्वारा: Chen, L, और अन्य
प्रकाशित: (2012)

ENDOPLASMIC RETICULUM AMINOPEPTIDASE-1 (ERAP1) PLAYS A CRITICAL ROLE IN PEPTIDE BINDING AND ANTIGEN PRESENTATION BY HLA-B27
द्वारा: Chen, L, और अन्य
प्रकाशित: (2012)

INVESTIGATING THE ROLE OF ENDOPLASMIC RETICULUM AMINOPEPTIDASE-1 (ERAP1) IN ANKYLOSING SPONDYLITIS
द्वारा: Chen, L, और अन्य
प्रकाशित: (2010)

INVESTIGATING THE ROLE OF ENDOPLASMIC RETICULUM AMINOPEPTIDASE-1 (ERAP1) IN ANKYLOSING SPONDYLITIS
द्वारा: Chen, L, और अन्य
प्रकाशित: (2010)

Identification of an unconventional sub-peptidome bound to the Behçet's disease - associated HLA-B*51:01 that is regulated by endoplasmic reticulum aminopeptidase 1 (ERAP1)
द्वारा: Chen, L, और अन्य
प्रकाशित: (2020)

To Be or Not to Be: The Case of Endoplasmic Reticulum Aminopeptidase 2
द्वारा: Piotr Kuśnierczyk
प्रकाशित: (2022-06-01)

Direct visualisation of HLA-B27 forms in cell lines and Spondyloarthropathy tissues
द्वारा: Rysnik, O, और अन्य
प्रकाशित: (2013)

EXPRESSION OF HLA-B27 HEAVY CHAIN FORMS IN ANKYLOSING SPONDYLITIS AND HLA-B27 POSITIVE CELL LINES
द्वारा: Rysnik, O, और अन्य
प्रकाशित: (2012)

HLA-B-27 heavy chain homodimer formation and natural killer cell family interaction - comparison of two HLA-B-27 subtypes in vitro
द्वारा: Giles, J, और अन्य
प्रकाशित: (2008)

The pathogenesis of spondyloarthritides - HLA-B-27 homodimer expression on human monocyte/macrophage cell lines
द्वारा: McHugh, K, और अन्य
प्रकाशित: (2008)

Silencing or inhibition of endoplasmic reticulum aminopeptidase 1 (ERAP1) suppresses free heavy chain expression and Th17 responses in ankylosing spondylitis.
द्वारा: Chen, L, और अन्य
प्रकाशित: (2015)

Crystal structures of the endoplasmic reticulum aminopeptidase-1 (ERAP1) reveal the molecular basis for N-terminal peptide trimming.
द्वारा: Kochan, G, और अन्य
प्रकाशित: (2011)

Impact of ACE and Endoplasmic Reticulum Aminopeptidases Polymorphisms on COVID-19 Outcome
द्वारा: Amany A. Ghazy, और अन्य
प्रकाशित: (2023-01-01)

HLA-B27 HEAVY CHAIN DIMER EXPRESSION IN SPONDYLOARTHRITIS
द्वारा: Rysnik, O, और अन्य
प्रकाशित: (2012)

HLA-B27 homodimers differ in their interactions with LILRB1, LILRB2, KIR3DL1 and KIR3DL2 compared to HLA-B27 heterotrimers
द्वारा: Giles, J, और अन्य
प्रकाशित: (2010)

Human leukocyte antigen B polymorphism and association between HLA‐B27 and endoplasmic reticulum aminopeptidase 1 rs30187 SNP in patients with ankylosing spondylitis in Bangladesh
द्वारा: Md Kamrul H. Sajib, और अन्य
प्रकाशित: (2022-03-01)

Endoplasmic reticulum aminopeptidase-1 polymorphism increases the risk of rheumatoid arthritis
द्वारा: Akbulut Ekrem, और अन्य
प्रकाशित: (2022-03-01)

Molecular Characterisation Of The Killer Cell Immunoglobulin-Like Receptor 3DL2 Binding To Aberrant HLA-B27 Heavy Chains In Spondyloarthritis
द्वारा: Hatano, H, और अन्य
प्रकाशित: (2013)

The KIRs of HLA-B27: the role of HLA-B27 KIR interactions in infection and spondyloarthritis
द्वारा: Wong-Baeza, I, और अन्य
प्रकाशित: (2011)

THE ARTHRITIS-ASSOCIATED HLA-B(star)27:05 FORMS MORE CELL SURFACE B27 DIMER AND FREE HEAVY CHAIN LIGANDS FOR KIR3DL2 AND LILRB2 IMMUNORECEPTORS THAN HLA(star)B27:09
द्वारा: Shaw, J, और अन्य
प्रकाशित: (2013)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
द्वारा: Bowness, P, और अन्य
प्रकाशित: (2010)

TARGETING MONOCYTE-EXPRESSED HLA-B27 HOMODIMERS IN ANKYLOSING SPONDYLITIS
द्वारा: Bowness, P, और अन्य
प्रकाशित: (2010)

THE ROLE OF HLA-B27 KIR3DL2 INTERACTIONS IN THE PATHOGENESIS OF SPONDYLOARTHRITIS
द्वारा: Kollnberger, S, और अन्य
प्रकाशित: (2012)

Factors determining the cell surface expression of a novel HLA-B27 epitope
द्वारा: McHugh, K, और अन्य
प्रकाशित: (2010)

The link between HLA-B27 and SpA--new ideas on an old problem.
द्वारा: McHugh, K, और अन्य
प्रकाशित: (2012)

Identification and characterisation of cell surface HLA-B27 homodimers
द्वारा: Bird, L, और अन्य
प्रकाशित: (2002)

HLA-B27 FORMS HEAVY CHAIN HOMODIMERS IN VITRO AND IN VIVO THAT BIND TO CELLULAR RECEPTORS INCLUDING LILR AND KIR FAMILY MEMBERS
द्वारा: McHugh, K, और अन्य
प्रकाशित: (2010)

Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply.
द्वारा: McHugh, K, और अन्य
प्रकाशित: (2014)

DIRECT VISUALIZATION OF HLA-B27 FORMS IN CELL LINES AND SPONDYLOARTHROPATHY TISSUES
द्वारा: Rysnik, O, और अन्य
प्रकाशित: (2013)

Interaction of HLA-B27 homodimers with KIR3DL1 and KIR3DL2, unlike HLA-B27 heterotrimers, is independent of the sequence of bound peptide.
द्वारा: Kollnberger, S, और अन्य
प्रकाशित: (2007)

Endoplasmic reticulum aminopeptidase 2 regulates CD4+ T cells pyroptosis in rheumatoid arthritis
द्वारा: Jianhua Zhang, और अन्य
प्रकाशित: (2024-01-01)

Association study of polymorphisms of endoplasmic reticulum aminopeptidase 1 gene with preeclampsia in Chinese populations
द्वारा: Cui Ma, और अन्य
प्रकाशित: (2021-08-01)

Endoplasmic reticulum aminopeptidase-1 functions regulate key aspects of the innate immune response.
द्वारा: Yasser A Aldhamen, और अन्य
प्रकाशित: (2013-01-01)

Residue Cys-67 of HLA-B27 contributes to antigen presentation and T cell recognition of HLA-B27 restricted T cell epitopes.
द्वारा: Appel, H, और अन्य
प्रकाशित: (2004)

Functional characterisation of HLA-B27 in autoimmunity
द्वारा: Kollnberger, S, और अन्य
प्रकाशित: (2001)

HLA-B27 transgenic rodents express cell surface HLA-B27 heavy chain homodimers and multimers.
द्वारा: Bowness, P, और अन्य
प्रकाशित: (2003)

Lymphoblastoid cells express HLA-B27 homodimers both intracellularly and at the cell surface following endosomal recycling.
द्वारा: Bird, L, और अन्य
प्रकाशित: (2003)

EnRAPtured: Is Endoplasmic Reticulum Aminopeptidase a New Clue to the Pathogenesis and ThERAPy of Uveitis?
द्वारा: James T. Rosenbaum, MD, और अन्य
प्रकाशित: (2021-09-01)

Association between Endoplasmic Reticulum Aminopeptidase-1 (ERAP-1) and Susceptibility to Ankylosing Spondylitis in Iran
द्वारा: Mahdi Mahmoudi, और अन्य
प्रकाशित: (2012-12-01)