Entorhinal‐based path integration selectively predicts midlife risk of Alzheimer's disease

INTRODUCTION: Entorhinal cortex (EC) is the first cortical region to exhibit neurodegeneration in Alzheimer's disease (AD), associated with EC grid cell dysfunction. Given the role of grid cells in path integration (PI)–based spatial behaviors, we predicted that PI impairment would represent th...

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Bibliographic Details
Main Authors: Newton, C, Pope, M, Rua, C, Henson, R, Ji, Z, Burgess, N, Rodgers, CT, Stangl, M, Dounavi, M, Castegnaro, A, Koychev, I, Malhotra, P, Wolbers, T, Ritchie, K, Ritchie, CW, O'Brien, J, Su, L, Chan, D
Format: Journal article
Language:English
Published: Wiley Open Access 2024