Remodelling of cortical actin where lytic granules dock at natural killer cell immune synapses revealed by super-resolution microscopy

Natural Killer (NK) cells are innate immune cells that secrete lytic granules to directly kill virus-infected or transformed cells across an immune synapse. However, a major gap in understanding this process is in establishing how lytic granules pass through the mesh of cortical actin known to under...

Descripción completa

Detalles Bibliográficos
Autores principales: Brown, A, Oddos, S, Dobbie, I, Alakoskela, J, Parton, R, Eissmann, P, Neil, M, Dunsby, C, French, P, Davis, I, Davis, D
Formato: Journal article
Lenguaje:English
Publicado: Public Library of Science 2011