Crystal structures of the extracellular domain from PepT1 and PepT2 provide novel insights into mammalian peptide transport

Mammals obtain nitrogen via the uptake of di- and tri-peptides in the gastrointestinal tract through the action of PepT1 and PepT2, which are members of the POT family of proton-coupled oligopeptide transporters. PepT1 and PepT2 also play an important role in drug transport in the human body. Recent...

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Bibliographic Details
Main Authors: Beale, J, Parker, J, Samsudin, F, Barrett, A, Senan, A, Bird, L, Scott, D, Owens, R, Sansom, M, Tucker, S, Meredith, D, Fowler, P, Newstead, S
Format: Journal article
Language:English
Published: Cell Press 2015