Inhibition studies on hypoxia-inducible factor (HIF) hydroxylases

<p>The hypoxia-inducible factor (HIF) is a key regulator of transcriptional responses to hypoxia in animals. As part of the cellular response to decreased oxygen concentrations, the transcriptional activity of a heterodimeric complex consisting of HIFα and HIFβ activates the expression of h...

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Bibliographic Details
Main Author: Chan, M
Other Authors: Schofield, C
Format: Thesis
Published: 2014