Automated structural comparisons clarify the phylogeny of the right-hand-shaped polymerases.

Polymerases are essential for life, being responsible for replication, transcription, and the repair of nucleic acid molecules. Those that share a right-hand-shaped fold and catalytic site structurally similar to the DNA polymerase I of Escherichia coli may catalyze RNA- or DNA-dependent RNA polymer...

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Bibliographic Details
Main Authors: Mönttinen, H, Ravantti, J, Stuart, D, Poranen, M
Format: Journal article
Language:English
Published: 2014