Synthesis and C-alkylation of hindered aldehyde enamines.
A new reactivity mode of hindered lithium amides with terminal epoxides is described whereby aldehyde enamines are produced via a previously unrecognized reaction pathway. Some of these aldehyde enamines display unprecedented C-alkylation reactivity toward unactivated primary and secondary alkyl hal...
Glavni autori: | Hodgson, D, Bray, C, Kindon, N, Reynolds, N, Coote, S, Um, J, Houk, K |
---|---|
Format: | Journal article |
Jezik: | English |
Izdano: |
2009
|
Slični predmeti
-
Enamines from terminal epoxides and hindered lithium amides.
od: Hodgson, D, i dr.
Izdano: (2004) -
Enantioenriched a-substituted aldehydes via diastereoselective enamine alkylation
od: Kaka, N, i dr.
Izdano: (2007) -
Asymmetric synthesis of alpha-alkylated aldehydes using terminal epoxide-derived chiral enamines.
od: Hodgson, D, i dr.
Izdano: (2008) -
Asymmetric synthesis of α-alkylated aldehydes using chiral enamines
od: Kaka, N, i dr.
Izdano: (2008) -
Transition states and origins of 1,4-asymmetric induction in alkylations of 2,2,6-trialkylpiperidine enamines.
od: Um, J, i dr.
Izdano: (2010)