Endothelial-specific Nox2 overexpression increases vascular superoxide and macrophage recruitment in ApoE⁻/⁻ mice.

AIMS: Vascular disease states are associated with endothelial dysfunction and increased production of reactive oxygen species derived from NADPH oxidases. However, it remains unclear whether a primary increase in superoxide production specifically in the endothelium alters the initiation or progress...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Douglas, G, Bendall, J, Crabtree, M, Tatham, A, Carter, E, Hale, AB, Channon, K
Format: Journal article
Sprache:English
Veröffentlicht: 2012