Endothelial-specific Nox2 overexpression increases vascular superoxide and macrophage recruitment in ApoE⁻/⁻ mice.
AIMS: Vascular disease states are associated with endothelial dysfunction and increased production of reactive oxygen species derived from NADPH oxidases. However, it remains unclear whether a primary increase in superoxide production specifically in the endothelium alters the initiation or progress...
Hauptverfasser: | , , , , , , |
---|---|
Format: | Journal article |
Sprache: | English |
Veröffentlicht: |
2012
|