Innate immune receptors for cross-presentation: The expanding role of NLRs
A critical role of pattern recognition receptors (PRRs) is to influence adaptive immune responses by regulating antigen presentation. Engagement of PRRs in dendritic cells (DCs) increases MHC class I antigen presentation and CD8+ T-cell activation by cross-presented peptides but the molecular mechan...
Main Authors: | , |
---|---|
Format: | Journal article |
Language: | English |
Published: |
Elsevier
2017
|