A prototypical Fanconi anemia pathway in lower eukaryotes?

DNA interstrand cross-links (ICLs) present a major challenge to cells, preventing separation of the two strands of duplex DNA and blocking major chromosome transactions, including transcription and replication. Due to the complexity of removing this form of DNA damage, no single DNA repair pathway h...

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Detalles Bibliográficos
Main Authors: McHugh, P, Ward, T, Chovanec, M
Formato: Journal article
Idioma:English
Publicado: 2012