Epigenetics in sepsis: understanding its role in endothelial dysfunction, immunosuppression, and potential therapeutics

Sepsis has a complex pathophysiology in which both excessive and refractory inflammatory responses are hallmark features. Pro-inflammatory cytokine responses during the early stages are responsible for significant endothelial dysfunction, loss of endothelial integrity, and organ failure. In addition...

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Bibliographic Details
Main Authors: Cross, D, Drury, R, Hill, J, Pollard, A
Format: Journal article
Language:English
Published: Frontiers Media 2019