Epigenetics in sepsis: understanding its role in endothelial dysfunction, immunosuppression, and potential therapeutics

Sepsis has a complex pathophysiology in which both excessive and refractory inflammatory responses are hallmark features. Pro-inflammatory cytokine responses during the early stages are responsible for significant endothelial dysfunction, loss of endothelial integrity, and organ failure. In addition...

Полное описание

Библиографические подробности
Главные авторы: Cross, D, Drury, R, Hill, J, Pollard, A
Формат: Journal article
Язык:English
Опубликовано: Frontiers Media 2019