Epigenetics in sepsis: understanding its role in endothelial dysfunction, immunosuppression, and potential therapeutics
Sepsis has a complex pathophysiology in which both excessive and refractory inflammatory responses are hallmark features. Pro-inflammatory cytokine responses during the early stages are responsible for significant endothelial dysfunction, loss of endothelial integrity, and organ failure. In addition...
| Hlavní autoři: | , , , |
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| Médium: | Journal article |
| Jazyk: | English |
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Frontiers Media
2019
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