Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability

Identification of a BRCA1-mRNA Splicing Complex Required for Efficient DNA Repair and Maintenance of Genomic Stability

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Mutations within BRCA1 predispose carriers to a high risk of breast and ovarian cancers. BRCA1 functions to maintain genomic stability through the assembly of multiple protein complexes involved in DNA repair, cell-cycle arrest, and transcriptional regulation. Here, we report the identification of a...

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Autors principals:	Savage, K, Gorski, J, Barros, E, Irwin, G, Manti, L, Powell, A, Pellagatti, A, Lukashchuk, N, McCance, D, McCluggage, W, Schettino, G, Salto-Tellez, M, Boultwood, J, Richard, D, McDade, S, Harkin, D
Format:	Journal article
Publicat:	2014

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