Tenascin-C fragments are endogenous inducers of cartilage matrix degradation.

Cartilage destruction is a hallmark of osteoarthritis (OA) and is characterized by increased protease activity resulting in the degradation of critical extracellular matrix (ECM) proteins essential for maintaining cartilage integrity. Tenascin-C (TN-C) is an ECM glycoprotein, and its expression is u...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Sofat, N, Robertson, S, Hermansson, M, Jones, J, Mitchell, P, Wait, R
Fformat: Journal article
Iaith:English
Cyhoeddwyd: 2012